Drugs Originating from the Screening of Organic Chemicals
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چکیده
The previous chapter dealt with a variety of drugs that can trace their origins to the screening of synthetic dyes for chemotherapeutic activity. Even more drugs have been discovered through the screening of other synthetic compounds. Screening has been used both to discover drug prototypes and to find improved analogues of other compounds that exhibit useful activity but require enhancement in some manner. Examples of the latter process can be found throughout this book, but the present chapter is concerned solely with the discovery of drug prototypes through screening and their subsequent development to provide therapeutic agents.
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